Legacy sequencing technologies have made comprehensive transcriptome analysis possible and are invaluable for the study of human genetics and mechanisms of diseases. However, these technologies struggle to generate full-length transcripts, require fragmentation and rely on converting RNA to cDNA.

Discover how Oxford Nanopore sequencing overcomes these limitations, delivering high outputs of any-length reads that span full-length RNA transcripts, resulting in complete transcriptome characterization at the isoform level.

Contents

In this White Paper, you will:

• Learn the importance of transcriptomics and its recent developments
• Discover the limitations of legacy sequencing technologies
• Find out how nanopore sequencing overcomes these limitations
• Read real-world case studies of how researchers are utilizing nanopore sequencing to deliver new insights